Table 2.

Suppression of E7–EJ-ras cooperation

Cell lineMean colony no. ± SDa% Reduction of transformation
E7 + EJ-ras85 ± 120
p53Pro b 50 ± 1241
p53Arg b 14 ± 483
  • a From five separate transfections.

  • b These cells were cotransfected with the p53 variants together with the EJ-ras and E7 oncogenes.