TABLE 1.

Cell DI of L cells expressing E-cadherin mutants in the presence or absence of IC261a

TreatmentDI (NTC/NTE)
Parental L cellL cell expressing E-cad (WT) WT2L cell expressing E-cad (S846A) A5L cell expressing E-cad (S846D) D13
− IC2610.83 ± 0.090.64 ± 0.09a0.46 ± 0.09**b0.88 ± 0.04***c
+ IC2610.91 ± 0.050.52 ± 0.05*d0.41 ± 0.09*e0.72 ± 0.06
  • a *, P < 0.05 (a and d, b and e); **, P < 0.01 (a and b); ***, P < 0.005 (a and c). The data were obtained from more than four independent experiments. E-cad, E-cadherin; WT, wild type.