TABLE 1.

KDM5b increases stem cell markers and proliferationa

Marker(s)mESC differentiation patternP value
% KDM5b% ControlFold change (KDM5b/control)
Oct4 Mito89.7495.280.97.5E-05
Mito+ Oct49.264.252.20.0002
Oct4+0.080.081.10.9
Oct4+ Mito+0.930.402.30.005
  • a Results of flow cytometry analysis of day 3 neurospheres showing the percentage of all live cells that stained with anti-Oct4 (Oct4) primary/Alexa 488 secondary and/or (Mito+) anti-P-H3/Alexa 647 secondary.