TABLE 3.

Putative TIAR target mRNAs bearing the C-rich signature motif in the 3′UTRa

Position(s) in 3′UTRbNameSymbolUnigene no.
1445-1472 (0.58), 2180-2207 (3.38), 2630-2659 (1.56)Sideroflexin 5SFXN5Hs#S4546027
1087-1115 (0.85), 1430-1457 (2.60), 1461-1488 (1.50), 1585-1612 (0.24)Ras-related protein Rab-40CRAB40CHs#S4044974
190-217 (3.95)Ribosomal protein L34RPL34Hs#S3940107
250-277 (3.60)Calcium-dependent protein kinase IGCAMK1GHs#S3619658
206-235 (1.30)Homolog of mouse LGP1LGP1Hs#S3619636
172-200 (1.14)Myosin, heavy polypeptide 9, non-muscleMYH9Hs#S3220052
1392-1419 (3.55)Microtubule-associated proteins 1A/1B light-chain 3BMAP1LC3BHs#S3219949
770-797 (3.12)Matrix metalloproteinase 25MMP25Hs#S3219838
683-710 (1.53)Junctophilin 3JPH3Hs#S3219743
135-164 (0.89), 556-583 (2.38)Phospholysine phospho-His inorganic pyrophosphate phosphataseLHPPHs#S3219695
62-89 (3.63)Prostate and breast cancer overexpressed 1PBOV1Hs#S3219375
140-167 (1.16)Potassium inwardly-rectifying channel, J11KCNJ11Hs#S3218881
828-853 (2.14)Solute carrier family 2 (facilitated glucose transporter), member 6SLC2A6Hs#S2294542
284-308 (2.73)Sphingosine kinase 2SPHK2Hs#S2294536
2014-2041 (3.10)Ring finger protein 144RNF144Hs#S2139432
1472-1501 (0.04), 2649-2677 (0.59), 3189-3216 (2.93)Protein phosphatase 1FPPM1FHs#S2139385
1308-1335 (3.66)Apoptotic protease-activating factorAPAF1Hs#S2138799
1839-1866 (1.31)ATPase, (Na+)/K+-transporting, beta 4 polypeptideATP1B4Hs#S1824340
431-459 (3.68)Poly(A) binding protein, nuclear 1PABPN1Hs#S1732404
318-345 (4.38)Interleukin-24IL-24Hs#S1732294
194-222 (1.53)Growth factor, augmenter of liver regeneration (ERV1 homolog)GFERHs#S1732174
975-1002 (3.31)Mitogen-activated protein kinase kinase kinase 14MAP3K14Hs#S1731892
287-314 (4.38)Polyamine-modulated factor 1PMF1Hs#S1731724
1013-1040 (3.21)Huntingtin-interacting protein 1-relatedHIP1RHs#S15639035
67-96 (0.38), 276-303 (3.80), 347-372 (0.24), 511-538 (2.12), 745-771 (1.33)Histamine receptor H3HRH3Hs#S1731688
13-40 (1.34)Neuro-oncological ventral antigen 2NOVA2Hs#S1731549
109-136 (3.34), 227-254 (0.17), 956-983 (2.38), 2107-2134 (0.23)SRY (sex-determining region Y)-box 12SOX12Hs#S1731519
1554-1583 (4.23), 2449-2476 (0.27)Calcium-dependent protein kinase 2CAMKK2Hs#S1731273
1218-1246 (1.31), 1960-1985 (0.80)NK3 transcription factor related, locus 1 (Drosophila)NKX3-1Hs#S1730286
101-128 (1.05), 859-886 (3.75)Signal-regulatory protein beta 1SIRPB1Hs#S1730130
240-267 (1.12)Brain-specific angiogenesis inhibitor 1BAI1Hs#S1729737
311-337 (0.99), 625-653 (0.78), 4921-4948 (0.95), 5654-5681 (2.12), 5818-5845 (1.25)Methyl CpG binding protein 2MECP2Hs#S1729484
809-836 (3.48)Vanin 1VNN1Hs#S1729359
51-78 (5.63), 660-689 (1.89), 785-812 (0.14), 841-868 (0.21), 3296-3326 (0.02), 3504-3531 (0.06)Synaptogyrin 1SYNGR1Hs#S1729312
1501-1528 (2.31)Eukaryotic translation termination factor 1ETF1Hs#S1729236
155-182 (3.63)Natural killer cell transcript 4NK4Hs#S1729141
357-384 (0.21), 773-801 (1.95), 1094-1125 (0.04)Paired box gene 2, transcript variant cPAX2Hs#S1728525
330-358 (0.76), 2112-2139 (0.62), 2211-2240 (2.46)Major histocompatibility complex class II transactivatorMHC2TAHs#S1728490
55-82 (2.12)Alpha-l-iduronidase precursorIDUAHs#S1728450
52-82 (3.79)Tu translation elongation factorTUFMHs#S1728121
663-690 (2.37)Transforming growth factor, beta receptor IIITGFBR3Hs#S1728020
290-317 (1.16)Syntrophin, alpha 1SNTA1Hs#S1727897
962-988 (1.34)Regulator of G-protein signaling 16RGS16Hs#S1727647
16-43 (3.16)RAB3B, member RAS oncogene familyRAB3BHs#S1727591
525-552 (0.73), 999-1027 (0.27), 1322-1351 (1.05)PaxillinPXNHs#S1727580
1734-1761 (1.44), 2017-2042 (1.56)Oligophrenin 1OPHN1Hs#S1727255
464-491 (1.12)Eukaryotic translation initiation factor 5EIF5AHs#S1726700
782-810 (1.95)C-terminal PDZ domain ligand of neuronal NOSCAPONHs#S15898574
32-59 (3.12)Transcription factor 3TCF3Hs#S11062708
  • a Shown is a partial list of genes bearing the C-rich signature motif in the 3′UTR of the corresponding transcripts. (The complete list of predicted target transcripts is available from the authors.)

  • b The relative positions of the C-rich TIAR motif within each transcript and the corresponding scores (in parentheses) are indicated.