TABLE 2.

Divergent MAZ motifs are abundant in striated muscle genes

GeneSpeciesDivergent MAZ motifsaPositions
Serum Response FactorMouseGGGAAGGG−6 to +2
CTCCTCCC−208 to −201
CTCCACCC−568 to −561
CCCCTCCA−571 to −564
Skeletal α-actinMouseGGGTGGAG+64 to +71
GGGAAGGG−83 to −76
CTCCTCCC−495 to −488
CTCCTCCC−680 to −673
β-MyHCMouseCCCTTCCC−480 to −473
CTCCTCCC−816 to −809
CTCCTCCC−860 to −853
Muscle creatine kinaseHumanCTCCTCCC−82 to −75
MouseCCCCTCAC−1564 to −1557
CTCCGCCC−1585 to −1578
Myosin light chain 2VMouseCTCCTCCC−433 to −426
CCCCTCCA−2451 to −2444
CCCCTACC−2276 to −2269
Six5MouseGGGCGGAG−286 to −279
GGGAAGGG−308 to −301
CTCCTCCC−357 to −350
VimentinMouseCTCCACCC−535 to −528
GGTAGGGG−925 to −918
CTCCTCCC−2055 to −2048
MEF2CMouseCTCCTCCC−113 to −106
GGGAGGAG−1200 to −1193
M1 muscarinic AChRRatCTCCTCCC+326 to + 333
CCCCTCCA−722 to −715
MyogeninMouseGGGAAGGG−153 to −146
CCCTTCCC−432 to −425
Neuronal AChR β4RatCTCCACCC−57 to −50
CCCTTCCC−63 to −56
Six4MouseCTCCTCCC−105 to −98
GGGTGGAG−152 to −145
CaChR α-1MouseCCCCTACC−190 to −183
MyoD (PRR)MouseCTCCGCCC−114 to −107
Six1HumanCTCCTCCC−497 to −490
TelokinMouseGGGCGGAG−1329 to −1322
  • a Sequences correspond to divergent MAZ motifs, shown in Fig. 7D, which have not been shown to bind Sp/KLF factors.