TABLE 1.

Summary of changes in secondary structural elements in AF1 after p38-mediated phosphorylationa

Element% Change
AF1AF1-PAF1S211AAF1S211A-P
α-Helix26452526
β-Sheet13191514
Random coil61366060
  • a Values were calculated from the CD data (Fig. 2) using the K2d algorithm (1, 30a). AF1, unphosphorylated AF1; AF1-P, phosphorylated AF1.