TABLE 1.

Genotyping analysis of F2 offspring from REA heterozygous mouse intercrossesa

Genetic background and genderNo. of F2 offspringNo. (%) of mice of genotype:
+/++/−−/−
Outbred260106 (41)154 (59)0 (0)
    Male1365878
    Female1244876
Inbred9737 (38)60 (62)0 (0)
    Male441628
    Female532132
  • a Results are shown for each genotype in two different genetic backgrounds (outbred, 129Sv × C57BL; inbred, 129Sv × 129Sv) as numbers of viable offspring derived from REA heterozygous matings.