TABLE 4.

Circulating metabolites in Akt3 knockout mice

Metabolic parameteraValue for malesValue for females
Wild-typeKnockoutWild-typeKnockout
Fasting insulin (ng/ml)0.363 ± 0.02140.399 ± 0.06010.365 ± 0.03940.427 ± 0.0539
Fasting glucose (mg/dl)72 ± 1.679 ± 3.179 ± 5.987 ± 5.9
Fed glucose (mg/dl)145 ± 5.6159 ± 11.4NDND
Fed FFA (mEq/liter)0.25 ± 0.0550.20 ± 0.0350.20 ± 0.0110.22 ± 0.032
Fasting FFA (mEq/liter)1.11 ± 0.0461.10 ± 0.1120.98 ± 0.0741.00 ± 0.062
  • a Data are means ± SD. N = 7 for each group. FFA, free fatty acids; ND, not done.