Table 2.

Identification of the nuclear retention and rim association determinants of hTAPa

hTAP aaGFP fusionGFP–β-Gal fusion
Nuclear accumulationNuclear rim associationLocal-izationNuclear rim association
1–619YesYesNYes
61–619YesYesNYes
61–619 S585PYesNo
61–619 S585AYesYes
140–619CYes
266–619YesYesCYes
266–619 S585PCNo
266–619 S585ACYes
375–619YesYes
375–560No
412–619YesYesCYes
412–560No
507–619No
540–619No
550–619No
566–619No
  • a N, nucleus; C, cytoplasm.