Table 1.

Expression of D-type cyclins, CDK4, CDK6, and CDK inhibitors in a panel of cell lines

Cell lineExpressiona of:
D1D2D3CDK4CDK6p15p16p18p19p21p27
ML1+++++++/−++++++
EL4++++++++++++++++++++++
CEM++++++++++++++
293++++++++++++++/−+/−
WI38+++++++++/−++/−+++
MCF7++++++++++++++
  • a +++, ++, +, +/−, and −, relative intensites of the signal, from strongest to below the level of detection with the available antisera.