Table 1.

Summary of nucleocytoplasmic distributions of U3 variantsa

U3 RNARetention in nucleus
Wild typeYes
Single variants
 5′ deletionYes
 ΔA′Yes
 ΔAYes
 ΔHYes
 ΔC′Yes
 ΔBYes
 ΔCYes
 ΔDYes
Double variants
 ΔA′BYes
 ΔA′CYes
 ΔAHYes
 ΔAC′Yes
 ΔACYes
 ΔADYes
 ΔHCYes
 ΔHDYes
 ΔC′BNo
 ΔC′CNo
 ΔC′DYes
 ΔBCYes
 ΔBDNo
 ΔCDNo
  • a The distribution of each RNA was analyzed over an 8-h time course (as described for Fig. 2).