Table 1.

Serum chemistry of HNF-1α knockout micea

Age (wk) and typeAST (U/liter)ALT (U/liter)Glucose (mg/dl)Cholesterol (mg/dl)Albumin (g/dl)Total protein (g/dl)
1
 +/−300 ± 1640 ± 7103 ± 799 ± 21.9 ± 0.13.1 ± 0.1
 −/−194 ± 2424 ± 5100 ± 689 ± 41.9 ± 0.13.1 ± 0.1
5
 +/−95 ± 1628 ± 2142 ± 29110 ± 203.5 ± 0.24.7 ± 0.1
 −/−121 ± 5787 ± 35287 ± 79286 ± 522.8 ± 0.24.3 ± 0.3
12
 +/−89 ± 2025 ± 4129 ± 30121 ± 193.4 ± 0.25.0 ± 0.2
 −/−243 ± 101242 ± 117332 ± 15307 ± 542.9 ± 0.24.5 ± 0.2
  • a Serum was collected from groups of mice of either genotype at three different ages and subjected to analysis for levels of AST, ALT, glucose, cholesterol, and albumin. Values presented are the means ± standard errors for at least four serum samples.