TABLE 1

Summary of protection from polyQ toxicity and spatial segregation of polyQ aggregates by DnaJB proteinsa

ProteinToxicity protectionSpatial segregation
DnaJB6++
JB6-D33N+
JB6-STC only+
JB6-ST only
JB6ΔST
JB6ΔC+
DnaJB6-7J+
DnaJB6-7C+/−+
DnaJB6-7ST+
DnaJB7
DnaJB7-6J
DnaJB7-6C−/+
  • a Figures 5 and 6 provide experimental data. +, yes; −, no; +/−, partial; −/+, noticeable but weak.