Table 2.

Proportion of IR-A mRNA in adult and fetal normal human tissues and in cultured dermal fibroblasts

Tissue or cell typeProportion (%) of IR-Aain:P
Fetal tissueAdult tissue
Brain51.5 ± 3.552.0 ± 2.50.627
Kidney52.5 ± 2.545.5 ± 0.50.008
Muscle47.0 ± 2.035.0 ± 5.00.017
Liver45.5 ± 0.528.5 ± 1.50.001
Fibroblasts78.2 ± 6.329.6 ± 9.20.001
  • a as determined by RT-PCR (mean ± standard error of triplicate measurements).