Table 4.

caf1 and ccr4 disruptions suppressnot-induced 3-AT phenotypesa

Relevant genotypeGrowth on 3-AT (mM)
0510
Wild type+
caf1 +
ccr4 +
not1-2 +++
not1-2 caf1 +w
not1-2 ccr4 +
not3-2 +++
not3-2 ccr4 +
not4 +++
not4 caf1 +
not4 ccr4 +
  • a All strains are isogenic to KY803 except for the indicated allele. Growth was monitored on minimal medium lacking histidine and supplemented with 3-AT as indicated.