Table 1.

Upregulation of DNA MTase RNA in Hut 78 cells during acute HIV infection

InfectionMTase RNA (relative units, 103)aProliferation (% of Hut 78)b
Hut 7822–48
Mock18–6394–96
NL43132–42583–90
HXB-2262–38085–88
  • a Determined 48 h postinfection with a PhosphorImager (Molecular Dynamics) by comparing integrated volumes of MTase RPA signals on gels to an internal standard, actin and/or cyclophilin. Data shown are ranges of three separate experiments.

  • b Measured 48 h postinfection by MTT assay (Promega) according to the manufacturer’s protocol. Data shown are ranges of three separate experiments.