Table 1.

Mitochondrial gene sets are differentially enriched in Mtm1gt/y muscle as determined by GSEA

Class systemSubclass titleP valuea
GOMitochondrial respiratory chain complex I4.04E-13
GOMitochondrial electron transport, NADH to ubiquinone4.04E-13
GOMitochondrial matrix4.04E-13
MetaCore GeneGo processesTranslation in mitochondria4.04E-13
MetaCore pathway mapsOxidative phosphorylation4.04E-13
GONADH dehydrogenase (ubiquinone) activity7.20E-12
MetaCore pathway mapsUbiquinone metabolism1.44E-11
GOElectron transport chain2.61E-10
GOTCA cycle5.74E-07
KEGG pathwaysCitrate cycle (TCA cycle), Homo sapiens (human)1.62E-05
GONADH dehydrogenase activity2.06E-05
KEGG pathwaysOxidative phosphorylation, Homo sapiens (human)2.14E-05
  • a The P value is the FDR-adjusted P value derived from the Kolmogorov-Smirnov statistic.