Table 1.

Testicular weight versus body weight in wild-type andINK4d-deficient micea

Mouse age and genotype (no. analyzed)bMean wt (SD) (g)Minimum wt (g)Maximum wt (g)
12 weeks old
 Testis WT (11)0.108 (0.015)0.0840.131
 Testis KO (13)0.067 (0.015)0.0450.104
 Body WT (9)25.9 (2.77)21.830.1
 Body KO (10)28.3 (2.07)24.831.0
14 weeks old
 Testis WT (13)0.111 (0.013)0.0890.136
 Testis KO (13)0.082.2 (0.018)0.0510.110
 Body WT (13)29.4 (2.90)25.234.1
 Body KO (13)27.1 (2.36)24.130.5
  • a Differences in testis weight were statistically significant between these two groups of animals (P < 0.01). Body weight, however, was not significantly different between wild-type andINK4d-deficient mice.

  • b Statistical analysis was performed by comparing testis weight and body weight from two groups of wild-type (WT) or INK4d-deficient (KO) animals of either 12 or 14 weeks of age.