Table 1.

T-cell differentiation and MHC I expression inUch-L3 mutant mice

Cell type% of CD4 CD8+cellsaSurface MHC I staining (arbitrary units)b
Thymus
 +/+7.98 ± 2.2848.31 ± 2.5
 −/−8.89 ± 3.1946.09 ± 1.15
Spleen
 +/+7.85 ± 1.2047.45 ± 2.7
 −/−6.50 ± 1.4349.71 ± 4.26
  • a Compared to the wild-type results, the percentage of CD4 CD8+ cells was increased by 10% (P, 0.30) in mutant thymus and reduced by 17% (P, 0.07) in mutant spleen (n = 5).

  • b Relative surface MHC I staining (arbitrary units) was decreased by 5% (P, 0.03) in mutant thymus and increased by 5% (P, 0.17) in mutant spleen (n = 5).