Table 1.

CAR response elementsa

PromoterType of repeatSequence
mRARβ2DR5 −530GATCCGGGTAG GGTTCACCGAAAGTTCA CTCGA−502
MMTVDR4/5 −123GGTTCCCA GGGTTAAAATAAGTTCA TCTAGA−94
rCYP3A1DR3 −1262GTAGA TGAACTTCATGAACT GTCTA−1238
hCYP3A4ER6 −930AGAATA TGAACTCAAAGGAGGTCA GTGAG−902
mCYP2B10-1DR4 −2336CCGAAC TGTACTTTCCTGACCT TGGCAC−2316
mCYP2B10-2DR4 −2304CCACCA TCAACTTGCCTGACAC AGGAA−2278
  • a Promoter sequences are from other references, as follows (reference numbers are in parentheses): mouse RARβ2 (mRARβ2) (37), MMTV (35), rat CYP3A1 (rCYP3A1) (22), human CYP3A4 (hCYP3A4) (10), and mouse CYP2B10 (mCYP2B10) (14). Boldface type indicates the hexamer consensus sequence, and underlining indicates the response element. The superscript numbers are nucleotide positions.