Table 3.

Some actin cortical patch mutations affectINT1-induced filamentous growth

Strain nameRelevant genotypeaNo. of INT1-induced filamentsbFilament shapec
YJB2714Wild type+++
YJB2715 abp1Δ +++wt
YJB3054Wild type+++
YJB3053 sac6Δ +++
YJB3321Wild type+++
YJB3329 srv2-100 +sh
YJB3331 bni1-100 +sh, shm
YJB2623Wild type+++
YJB2622 vrp1Δ +sh
YJB3057Wild type+++
YJB3056 rvs167Δ ++sh
YJB3156wild type++++
YJB3155 sla1-Δ1 +sh
YJB3156Wild type+++
YJB3157 sla2Δ +sh
  • a Complete genotypes of the strains are listed in Table 1.

  • b Relative proportion of cells exhibitingINT1-induced filaments. In each case, the strain was compared with the appropriate isogenic or congenic wild-type strain listed in Table 1. +++, similar to wild type; ++, ∼25 to 75% of wild-type levels; +, less than 25% of wild-type levels of filament formation.

  • c Appearance of filaments relative to how they appeared in the isogenic or congenic wild-type strains. wt, filaments were indistinguishable from wild-type filaments; sh, average filament length was shorter than in the relevant wild-type strain; shm, polarized cells appeared similar to mating projections (shmoos).