Table 1.

Comparison of blood component levels in wild-type and RGL knockout micea

Blood component levelWild-type littermatesRGL null mutants
MaleFemalesMaleFemale
Blood glucose, fasted (mg/dl)74.8 ± 7.370.0 ± 9.788.9 ± 9.460.5 ± 4.7
Blood glucose, fed (mg/dl)131.3 ± 9.4135.8 ± 7.0142.8 ± 9.0140.0 ± 4.9
Serum insulin (μg/ml)0.72 ± 0.140.46 ± 0.070.62 ± 0.110.46 ± 0.10
Serum lactate (mM)5.93 ± 0.864.77 ± 0.635.90 ± 1.495.16 ± 0.45
Serum triglycerides (mg/dl)94.4 ± 5.376.5 ± 12.698.5 ± 15.488.0 ± 9.3
  • a Mice were 12 to 24 weeks old. The number of animals per group was 4 to 8. No significant differences were observed between the values for comparable groups of wild-type and knockout animals using Student's t test.