Table 2.

Repair classes of DSB-induced interchromosomal recombination

Repair classNo. of clones
F5′/3′R5′/3′
Gene conversion without an exchange
 I (conversion tract, <0.2 kb)a 00
 II (conversion tract, <1.0 kb)2924
 III (conversion tract, <3.2 kb)41
 IV (conversion tract, >3.2 kb)129
Translocation01b
Total4535
  • a Gene conversion tracts of less than 229 bp do not produce a functional neo + gene, and thus these products are not recovered.

  • b The translocation was between chr.17 and an unidentified chromosome(s) (see Fig. 4B).