Table 2.

Chromosomal locations of human PTP genes and their genomic clonesa

Protein nameChrBandEnsembl gene IDGenomic clones (EMBL accession no.)
hLyPTP1p13.1ENSG00000081021 AL365321,AL137856
hLAR1p34.2c AL158083
hPTPlambda1p35.2ENSG00000060656 AL049570
hCD451q32.1ENSG00000081237 AL355988
hHePTP1q32.1b
hPTPD21q41ENSG00000065995 AC026065,AC068586
hMEG12q14.2 AC016691
hBDP12q21.2ENSG00000072135 AC068137
hPTPIA22q35AC60820
hPTPgamma3p14.2 AC024885
pHDPTP3p25.1 AC023230
hPTPBAS4q22.1 AC007525,AC079237
hPTPkappa6q22.33 AL035465
hPEST7q11.23ENSG00000127947 AC006451,AC090421
hPTPzeta7q31.33ENSG00000106278 AC073471,AC006020
hPTPIA2beta7q36.3ENSG00000002748 AC005481,AC006372,AC006321
hPTPdelta9p23ENSG00000099228 AC026466
hPTPH19q32 AL359963,AL450025,AC013568
hPTPTyp10q11.22ENSG00000126542 AL358791
hPTPepsilon10q26.2ENSG00000132334 AL390236
hDEP111p11.2 AC026975
hSTEP11p15.1ENSG0000110786 AC016750
hGLEPP112p12.3ENSG00000084474 AC007542
hSHP112p13.31ENSG00000111679 AC006512,U47924, M86525,U72506
hPCPTP112q15ENSG00000111585 AC055123,AC083809, AC015544, AC090676, AC090670
hPTPbeta12q15 AC015544,AC083809, AC011053,AC025569
hPTPS3112q21.31ENSG00000091041 AC078825,AC074031
hSHP212q24.13ENSG00000089131 AC004086,AC004216
hPTPD114q31.3 AL353786,AL162171,AL049834
hMEG215q23 AC009712
hTCPTP18p11.21ENSG00000128772 AP001077,AC007734,AP002449
hPTPmu18p11.22ENSG00000069927 AC006566,AC021310, AP001094, AC069097, AC023663
hPTPsigma19p13.3ENSG00000105426 AC005338,AC005788
hSAP119q13.42ENSG00000080031 AC010327,AC010619
hPTPalpha20p13ENSG00000037980 AL121905,AL138803
hPTPrho20q12ENSG00000087530 AL024473
hPTP1B20q13.13ENSG00000063920 AL133230,AL034429
  • a The PTP amino acid sequences of the proteins were searched against those in the human genome databases (www.genome.ucsc.edu and www.ensembl.org) in order to determine their chromosomal locations (chromosome number [Chr] and band). Genomic clones for the human PTP genes (annotated genes in Ensembl and EMBL accession numbers) are hyperlinked to their respective databases (seehttp://science.novonordisk.com/ptp for the electronic version of the table).

  • b No genomic clones were found. Chromosomal localization was determined by fluorescent in situ hybridization (93).

  • c —, no gene annotation in Ensembl has been available so far.