TABLE 1.

Quantitation of retinoids in livera

GroupGenotypeall-trans-RA (ng/g)all-trans-Retinol (μg/g)Retinyl esters (μg/g)
UntreatedWild type1.5 ± 0.28.5 ± 1.0571 ± 59
Raldh1−/−1.6 ± 0.314.4 ± 1.22b1,278 ± 68c
Retinol treatedWild type3,100 ± 48019.5 ± 0.2570 ± 10
Raldh1−/−990 ± 60b36.2 ± 3.2c1,244 ± 57c
  • a Liver from mice treated with retinol (50 mg/kg) was examined 2 h after oral dosing. All values are means ± standard errors. (n = 4).

  • b P < 0.05 (Student's t test).

  • c P < 0.01 (Student's t test).