TABLE 3.

Lymphocyte populations in Tssc6-deficient micea

TissueLymphocyte subsetGenotype
Tssc6+/+Tssc6gt/gt
Bone marrowB220+ IgM46 ± 945 ± 9
B220low IgM+23 ± 623 ± 5
B220high IgM+16 ± 512 ± 4
BloodB220+ IgM+36 ± 1239 ± 11
CD4+34 ± 1135 ± 8
CD8+15 ± 315 ± 4
SpleenB220+ IgM+50 ± 547 ± 5
CD4+17 ± 219 ± 4
CD8+15 ± 216 ± 3
Lymph nodeB220+ IgM+24 ± 220 ± 2
CD4+49 ± 252 ± 2
CD8+21 ± 323 ± 2
Peritoneal cavityB220low CD5+43 ± 1837 ± 18
B220high IgM+26 ± 2122 ± 14
  • a Values (means ± standard deviations) represent the percentage of lymphocytes (based on forward and side scatter properties) that expressed the indicated cell surface marker. Values are derived from five animals of each genotype.