TABLE 3.

Comparison of median survival of frk/rak-null mice over 14 days after exposure to 10 Gy of radiationa

Dose (Gy)Median survival in days for genotype:Statistical significance
+/++/−−/−
1010.710.710.9>0.50b
>0.50c
>0.50d
0.99e
  • a Data is cumulative from two separate trials. Cohorts consist of 9.5- to 11-week-old age-matched littermates generated by heterozygous intercrosses.

  • b P value for +/+ versus +/− mice is given.

  • c P value for +/− versus −/− mice is given.

  • d P value for +/+ versus −/− mice is given.

  • e P value for +/+ and +/− versus −/− mice is given.