TABLE 1.

Hematological profile of Tssc6-null micea

Hematological parameterValue for the following genotype:
Tssc6+/+Tssc6gt/gt
Peripheral blood
    Hematocrit (%)46 ± 5747 ± 2
    Red blood cell reticulocytes (%)4 ± 23 ± 1
    White blood cell count (106/ml)6 ± 26 ± 2
        Neutrophils1 ± 0.41 ± 0.3
        Lymphocytes5 ± 25 ± 2
        Monocytes0.2 ± 0.20.1 ± 0.1
        Eosinophils0.1 ± 0.20.1 ± 0.1
    Platelets (106/ml)958 ± 2121,014 ± 227
Bone marrow
    Cellularity (106 cells/femur)31 ± 1433 ± 13
    Blasts (%)2 ± 12 ± 1
    Promyelocytes/myelocytes (%)4 ± 34 ± 2
    Metamyelocytes/neutrophils (%)46 ± 541 ± 8
    Lymphocytes (%)28 ± 528 ± 7
    Monocytes (%)6 ± 26 ± 2
    Eosinophils (%)3 ± 24 ± 1
    Nucleated erythroid cells (%)11 ± 315 ± 7
Spleen
    Wt (mg)79 ± 1867 ± 16
    Blasts (%)1 ± 11 ± 1
    Promyelocytes/myelocytes (%)0.5 ± 11 ± 1
    Metamyelocytes/neutrophils (%)4 ± 23 ± 2
    Lymphocytes (%)88 ± 688 ± 3
    Monocytes (%)2 ± 12 ± 2
    Eosinophils (%)0.5 ± 11 ± 1
    Nucleated erythroid cells (%)4 ± 34 ± 3
  • a Data given are means ± standard deviations of the specified hematological parameters from 6 to 12 mice of each genotype.