TABLE 1.

Absolute cell numbers of CD3+ (T) and B220+ (B) cells and CD4+ and CD8+ T cells in lymph nodes and spleens of c-FLIPL Tg mice (line 1) and NLCa

Cell typeValue for:
Lymph node (106)Spleen (106)
NLC (n = 7)c-FLIPL Tg (n = 7)NLC (n = 7)c-FLIPL Tg (n = 7)
CD3+ cells1.53 ± 0.431.45 ± 0.3328.5 ± 1.1518.6 ± 0.61
B220+ cells0.67 ± 0.421.37 ± 0.4358.1 ± 7.7650.2 ± 0.52
Ratio T/B2.30 ± 0.61.08 ± 0.20.50 ± 0.10.37 ± 0.1
CD3+ gate
    CD4+ T cells0.86 ± 0.050.94 ± 0.0619.3 ± 0.5414.3 ± 0.9
    CD8+ T cells0.63 ± 0.040.44 ± 0.057.81 ± 0.633.16 ± 0.8
    Ratio CD4/CD81.37 ± 0.32.14 ± 0.62.47 ± 0.354.52 ± 0.2
  • a Spleens and inguinal lymph nodes of 8- to 12-week-old mice were removed, and lymphocytes were counted. The number of cells in each subset was calculated from flow cytometric analysis of two- and three-color immunofluorescence on 10,000 cells per sample. Values are the means ± standard deviations.