TABLE 1.

Activation by AR coactivatorsalegend

CoactivatorActivation (fold)
Wild-type ARARK630QARK630T
ARA555.27.213.5
ARA706.17.59.6
SRC-13.37.710.9
TIP604.26.610.2
Ubc-920.129.872.0
  • legend aThe MMTV-Luc reporter was transfected into DU145 cells with the expression vector for hAR and the AR coactivators as detailed in Materials and Methods, and cells were treated with DHT (10−7 M) for 24 h. Data are means ± standard errors of the means compared with the control empty expression vector.