TABLE 1.

Morphometric analysis of WT and ERβ−/− mouse lungsa

Mouse descriptionNo. of alveoli/fieldNo. of nuclei/no. of alveoli
Female, 4 wk
    WT338 ± 192.66 ± 0.04
    ERβ−/−317 ± 56 (NS)2.69 ± 0.10 (NS)
Female, 3 mo
    WT433 ± 862.70 ± 0.26
    ERβ−/−309 ± 44*2.75 ± 0.36 (NS)
Male, 3 mo
    WT306 ± 272.71 ± 0.36
    ERβ−/−301 ± 16 (NS)2.67 ± 0.18 (NS)
  • a Data are means ± standard deviations (n = 4). *, P < 0.05; NS, not significant (unpaired Student's t test).