TABLE 1.

Summary of findings with apoJ/clusterin-deficient micea

CharacteristicResults
4 wk6 mo6 mo, UNX21 mo
Mesangial expansionNoNoYesYes
EM depositsNoNoYesYes
Immunofluorescence:
    IgG2+2+2+2+
    IgM3+3+3+3+
    IgA1+1+1+2+
    C1qNDND2+1+
    C3003+1+
    C9NDND03+
  • a ND, not done; UNX, uninephrectomy. n = 3 mice for each time point. See Materials and Methods for an explanation of scoring.