TABLE 1.

Classification of the α-satellite DNA immunoprecipitated with anti-CENP-A antibodiesa

Suprachromosomal familyChromosome no.Consensus sequenceNo. of clones% Homology
11, 3, 5, 6, 7, 10, 12, 16, 19J2(+), J1(−)4182-94
22, 4, 8, 9, 13, 14, 15, 18, 20, 21, 22D1(+), D2(−)4382-92
311, 17, XA(+), B(+), C(+), D(−), E(−)675-98
1, 2, or 3476-80
  • a α-Satellite clones recovered by immunoprecipitation with anti-CENP-A antibodies were classified into three suprachromosomal families (1). α-Satellite monomers with a CENP-B box are indicated by +, and monomers without the CENP-B box are marked by −. Each clone was highly homologous to one of the three families. Four clones could not be classified because they were equally homologous to all three families.