TABLE 1.

Michaelis-Menten kinetic analysis of CBP acetylation of oligonucleosomes in the presence or absence of Ztaa

Expt no.Km (mM)Vmax (min−1)
− Zta+ Zta− Zta+ Zta
13.2 × 10−33.2 × 10−41.2 × 10−32.0 × 10−3
23.2 × 10−31.2 × 10−53.9 × 10−47.4 × 10−4
33.0 × 10−35.3 × 10−54.5 × 10−49.4 × 10−4
  • a Lineweaver-Burk plot analysis was used to generate quantities for Km and Vmax.