TABLE 1.

Mitotic index in cells transfected with GL2 or GEM siRNAa

Cells% Mitotic cells (no. of cells counted)
GL2- transfected cells with small nucleiGEM- transfected cells with small nucleiGEM- transfected cells with giant nuclei
HCT116 (p53+/+)15 (300)3 (100)0 (120)
HCT116 (p53−/−)10 (350)2 (100)0 (120)
  • a Cells with phosphohistone H3 foci were regarded as mitotic cells.