TABLE 1.

Number of neutrophils and albumin concentration in pleural lavage fluid

Time (h) and treatmentNeutrophils (104)aAlbumin (mg/ml)a
Nrf2+/+ miceNrf2−/− miceNrf2+/+ miceNrf2−/− mice
01 ± 01 ± 00.27 ± 0.070.30 ± 0.14
12
    Vehicle179 ± 53c128 ± 480.38 ± 0.140.26 ± 0.09
    Carrageenan492 ± 59b,c508 ± 56b,c0.68 ± 0.22b,c0.87 ± 0.36b,c
24
    Vehicle27 ± 1821 ± 140.30 ± 0.180.31 ± 0.22
    Carrageenan229 ± 10b,c386 ± 56b,c1.1 ± 0.30b,c1.5 ± 0.26b,c
  • a Data are means ± SEM. At least three mice were examined for each group.

  • b Significantly different from time-matched vehicle control mice (P < 0.05).

  • c Significantly different from genotype-matched 0-h control mice (P < 0.05).