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angiogenesis

  • CCN1–Yes-Associated Protein Feedback Loop Regulates Physiological and Pathological Angiogenesis
    Research Article | Spotlight
    CCN1–Yes-Associated Protein Feedback Loop Regulates Physiological and Pathological Angiogenesis

    Cellular communication network factor 1 (CCN1) is a dynamically expressed, matricellular protein required for vascular development and tissue repair. The CCN1 gene is a presumed target of Yes-associated protein (YAP), a transcriptional coactivator that regulates cell growth and organ size.

    Sangmi Lee, Afruja Ahad, Michele Luu, Sohyun Moon, JoyAnn Caesar, Wellington V. Cardoso, Maria B. Grant, Brahim Chaqour
  • Loss of Estrogen-Related Receptor Alpha Facilitates Angiogenesis in Endothelial Cells
    Research Article | Spotlight
    Loss of Estrogen-Related Receptor Alpha Facilitates Angiogenesis in Endothelial Cells

    Estrogen-related receptors (ERRs) have emerged as major metabolic regulators in various tissues. However, their expression and function in the vasculature remains unknown.

    Neah Likhite, Vikas Yadav, Eric J. Milliman, Danesh H. Sopariwala, Sabina Lorca, Nithya P. Narayana, Megha Sheth, Erin L. Reineke, Vincent Giguère, Vihang Narkar
  • Open Access
    Research Article
    Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation
    Ayano Kondo, Aya Nonaka, Teppei Shimamura, Shogo Yamamoto, Tetsuo Yoshida, Tatsuhiko Kodama, Hiroyuki Aburatani, Tsuyoshi Osawa
  • Research Article | Spotlight
    let-7 Contributes to Diabetic Retinopathy but Represses Pathological Ocular Angiogenesis
    Qinbo Zhou, Robert J. A. Frost, Chastain Anderson, Fangkun Zhao, Jing Ma, Bo Yu, Shusheng Wang
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