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DNA Breaks, Double-Stranded

  • Research Article
    MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks
    Abid R. Mattoo, Raj K. Pandita, Sharmistha Chakraborty, Vijaya Charaka, Kalpana Mujoo, Clayton R. Hunt, Tej K. Pandita
  • Articles | Spotlight
    Requirement for the Phospho-H2AX Binding Module of Crb2 in Double-Strand Break Targeting and Checkpoint Activation
    Steven L. Sanders, Ahmad R. Arida, Funita P. Phan
  • Articles | Spotlight
    BRCT Domain Interactions with Phospho-Histone H2A Target Crb2 to Chromatin at Double-Strand Breaks and Maintain the DNA Damage Checkpoint
    Sevil Sofueva, Li-Lin Du, Oliver Limbo, Jessica S. Williams, Paul Russell
  • Articles | Spotlight
    The Expression Profile of the Major Mouse SPO11 Isoforms Indicates that SPO11β Introduces Double Strand Breaks and Suggests that SPO11α Has an Additional Role in Prophase in both Spermatocytes and Oocytes
    Marina A. Bellani, Kingsley A. Boateng, Dianne McLeod, R. Daniel Camerini-Otero
  • Articles
    MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair
    Girdhar G. Sharma, Sairei So, Arun Gupta, Rakesh Kumar, Christelle Cayrou, Nikita Avvakumov, Utpal Bhadra, Raj K. Pandita, Matthew H. Porteus, David J. Chen, Jacques Cote, Tej K. Pandita
  • Articles
    Effect of Telomere Proximity on Telomere Position Effect, Chromosome Healing, and Sensitivity to DNA Double-Strand Breaks in a Human Tumor Cell Line
    Avanti Kulkarni, Oliver Zschenker, Gloria Reynolds, Douglas Miller, John. P. Murnane
  • Articles
    Loss of YY1 Impacts the Heterochromatic State and Meiotic Double-Strand Breaks during Mouse Spermatogenesis
    Su Wu, Yueh-Chiang Hu, Huifei Liu, Yang Shi
  • Articles
    Meiotic DNA Double-Strand Break Repair Requires Two Nucleases, MRN and Ctp1, To Produce a Single Size Class of Rec12 (Spo11)-Oligonucleotide Complexes
    Neta Milman, Emily Higuchi, Gerald R. Smith
  • Articles
    Base Flipping in V(D)J Recombination: Insights into the Mechanism of Hairpin Formation, the 12/23 Rule, and the Coordination of Double-Strand Breaks
    Julien Bischerour, Catherine Lu, David B. Roth, Ronald Chalmers
  • Articles
    Locally, Meiotic Double-Strand Breaks Targeted by Gal4BD-Spo11 Occur at Discrete Sites with a Sequence Preference
    Hajime Murakami, Alain Nicolas

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