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Down-Regulation

  • Research Article
    A High-Fat Diet Promotes Mammary Gland Myofibroblast Differentiation through MicroRNA 140 Downregulation
    Benjamin Wolfson, Yongshu Zhang, Ramkishore Gernapudi, Nadire Duru, Yuan Yao, Pang-Kuo Lo, Qun Zhou
  • Research Article
    Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice
    Mikko N. M. Myllymäki, Jenni Määttä, Elitsa Y. Dimova, Valerio Izzi, Timo Väisänen, Johanna Myllyharju, Peppi Koivunen, Raisa Serpi
  • Articles | Spotlight
    Ikaros and Aiolos Inhibit Pre-B-Cell Proliferation by Directly Suppressing c-Myc Expression
    Shibin Ma, Simanta Pathak, Malay Mandal, Long Trinh, Marcus R. Clark, Runqing Lu
  • Articles | Spotlight
    14-3-3τ Regulates Ubiquitin-Independent Proteasomal Degradation of p21, a Novel Mechanism of p21 Downregulation in Breast Cancer
    Bing Wang, Kang Liu, Hui-Yi Lin, Naresh Bellam, Shiyun Ling, Weei-Chin Lin
  • Articles
    β-TrCP-Mediated Ubiquitination and Degradation of PHLPP1 Are Negatively Regulated by Akt
    Xin Li, Jianyu Liu, Tianyan Gao
  • Articles
    Human UPF1 Participates in Small RNA-Induced mRNA Downregulation
    Hua Jin, Mi Ra Suh, Jinju Han, Kyu-Hyeon Yeom, Yoontae Lee, Inha Heo, Minju Ha, Seogang Hyun, V. Narry Kim
  • Articles
    Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling Pathway
    Okay Saydam, Yiping Shen, Thomas Würdinger, Ozlem Senol, Elvan Boke, Marianne F. James, Bakhos A. Tannous, Anat O. Stemmer-Rachamimov, Ming Yi, Robert M. Stephens, Cornel Fraefel, James F. Gusella, Anna M. Krichevsky, Xandra O. Breakefield
  • Articles
    MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets
    Minh T. N. Le, Huangming Xie, Beiyan Zhou, Poh Hui Chia, Pamela Rizk, Moonkyoung Um, Gerald Udolph, Henry Yang, Bing Lim, Harvey F. Lodish
  • Articles
    The Transcription Factor COUP-TFII Is Negatively Regulated by Insulin and Glucose via Foxo1- and ChREBP-Controlled Pathways
    Anaïs Perilhou, Cécile Tourrel-Cuzin, Ilham Kharroubi, Carole Henique, Véronique Fauveau, Tadahiro Kitamura, Christophe Magnan, Catherine Postic, Carina Prip-Buus, Mireille Vasseur-Cognet
  • Articles
    Downregulation of Vertebrate Tel (ETV6) and Drosophila Yan Is Facilitated by an Evolutionarily Conserved Mechanism of F-Box-Mediated Ubiquitination
    M. Guy Roukens, Mariam Alloul-Ramdhani, Setareh Moghadasi, Marjolein Op den Brouw, David A. Baker

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