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Embryo Loss

  • Articles
    Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP
    Yei-Tsung Chen, Matthew M. Hims, Ranjit S. Shetty, James Mull, Lijuan Liu, Maire Leyne, Susan A. Slaugenhaupt
  • Articles
    Early Embryonic Lethality of Mice Lacking ZO-2, but Not ZO-3, Reveals Critical and Nonredundant Roles for Individual Zonula Occludens Proteins in Mammalian Development
    Jianliang Xu, P. Jaya Kausalya, Dominic C. Y. Phua, Safiah Mohamed Ali, Zakir Hossain, Walter Hunziker
  • Articles
    Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
    Ryan T. Dackor, Kimberly Fritz-Six, William P. Dunworth, Carrie L. Gibbons, Oliver Smithies, Kathleen M. Caron
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Complete Loss of Ndel1 Results in Neuronal Migration Defects and Early Embryonic Lethality
    Shinji Sasaki, Daisuke Mori, Kazuhito Toyo-oka, Amy Chen, Lisa Garrett-Beal, Masami Muramatsu, Shuji Miyagawa, Noriko Hiraiwa, Atsushi Yoshiki, Anthony Wynshaw-Boris, Shinji Hirotsune
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Disruption of the Mouse mTOR Gene Leads to Early Postimplantation Lethality and Prohibits Embryonic Stem Cell Development
    Yann-Gaël Gangloff, Matthias Mueller, Stephen G. Dann, Petr Svoboda, Melanie Sticker, Jean-Francois Spetz, Sung Hee Um, Eric J. Brown, Silvia Cereghini, George Thomas, Sara C. Kozma
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Placental Failure and Impaired Vasculogenesis Result in Embryonic Lethality for Neuropathy Target Esterase-Deficient Mice
    Markus Moser, Yong Li, Kristina Vaupel, Doris Kretzschmar, Reinhart Kluge, Paul Glynn, Reinhard Buettner
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Embryonic Lethality, Decreased Erythropoiesis, and Defective Octamer-Dependent Promoter Activation in Oct-1-Deficient Mice
    Victoria E. H. Wang, Tara Schmidt, Jianzhu Chen, Phillip A. Sharp, Dean Tantin
  • GENE EXPRESSION
    Dnmt1 Overexpression Causes Genomic Hypermethylation, Loss of Imprinting, and Embryonic Lethality
    Detlev Biniszkiewicz, Joost Gribnau, Bernard Ramsahoye, François Gaudet, Kevin Eggan, David Humpherys, Mary-Ann Mastrangelo, Zhan Jun, Jörn Walter, Rudolf Jaenisch
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Targeted Mutagenesis of the Hira Gene Results in Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives Prior to Early Embryonic Lethality
    Catherine Roberts, Helen F. Sutherland, Hannah Farmer, Wendy Kimber, Stephanie Halford, Alisoun Carey, Joshua M. Brickman, Anthony Wynshaw-Boris, Peter J. Scambler
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Embryonic Lethality Caused by Apoptosis during Gastrulation in Mice Lacking the Gene of the ADP-Ribosylation Factor-Related Protein 1
    A. G. Mueller, M. Moser, R. Kluge, S. Leder, M. Blum, R. Büttner, H.-G. Joost, A. Schürmann
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