Islets of Langerhans
- Research Article | SpotlightMorphogenesis of the Islets of Langerhans Is Guided by Extraendocrine Slit2 and Slit3 Signals
The spatial architecture of the islets of Langerhans is vitally important for their correct function, and alterations in islet morphogenesis often result in diabetes mellitus. We have previously reported that Roundabout (Robo) receptors are required for proper islet morphogenesis.
- MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPESAbnormal Glucose Homeostasis and Pancreatic Islet Function in Mice with Inactivation of the Fem1b Gene
- MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPESMafA Is a Key Regulator of Glucose-Stimulated Insulin Secretion
- SIGNAL TRANSDUCTIONCyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth