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lipolysis

  • Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor
    Research Article | Spotlight
    Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor

    Oxygen is a key molecule for efficient energy production in living organisms. Although aerobic organisms have adaptive processes to survive in low-oxygen environments, it is poorly understood how lipolysis, the first step of energy production from stored lipid metabolites, would be modulated during hypoxia.

    Ji Seul Han, Jung Hyun Lee, Jinuk Kong, Yul Ji, Jiwon Kim, Sung Sik Choe, Jae Bum Kim
  • Transient Overexpression of Vascular Endothelial Growth Factor A in Adipose Tissue Promotes Energy Expenditure via Activation of the Sympathetic Nervous System
    Research Article | Spotlight
    Transient Overexpression of Vascular Endothelial Growth Factor A in Adipose Tissue Promotes Energy Expenditure via Activation of the Sympathetic Nervous System

    Adipose-derived vascular endothelial growth factor A (VEGF-A) stimulates functional blood vessel formation in obese fat pads, which in turn facilitates healthy expansion of the adipose tissue. However, the detailed mechanism(s) governing the process remains largely unknown.

    Yueshui Zhao, Xin Li, Li Yang, Kristin Eckel-Mahan, Qingchun Tong, Xue Gu, Mikhail G. Kolonin, Kai Sun
  • Research Article | Spotlight
    Membrane Trafficking Protein CDP138 Regulates Fat Browning and Insulin Sensitivity through Controlling Catecholamine Release
    Qiong L. Zhou, Ye Song, Chun-Hong Huang, Jun-Yuan Huang, Zhenwei Gong, Zhangping Liao, Andria G. Sharma, Lily Greene, Justin Z. Deng, Michael C. Rigor, Xiangyang Xie, Songtao Qi, Julio E. Ayala, Zhen Y. Jiang
  • Research Article
    Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue
    Shui-Rong Zhou, Liang Guo, Xu Wang, Yang Liu, Wan-Qiu Peng, Yuan Liu, Xiang-Bo Wei, Xin Dou, Meng Ding, Qun-Ying Lei, Shu-Wen Qian, Xi Li, Qi-Qun Tang
  • Articles
    Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway
    Sarah M. Choi, David F. Tucker, Danielle N. Gross, Rachael M. Easton, Lisa M. DiPilato, Abigail S. Dean, Bob R. Monks, Morris J. Birnbaum
  • Articles
    The ARF-Like GTPase ARFRP1 Is Essential for Lipid Droplet Growth and Is Involved in the Regulation of Lipolysis
    Angela Hommel, Deike Hesse, Wolfgang Völker, Alexander Jaschke, Markus Moser, Thomas Engel, Matthias Blüher, Claudia Zahn, Alexandra Chadt, Karen Ruschke, Heike Vogel, Reinhart Kluge, Horst Robenek, Hans-Georg Joost, Annette Schürmann
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