liver X receptor
- Research ArticleCommon and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages
The liver X receptors α and β (LXRα and LXRβ) are oxysterol-activated transcription factors that coordinately regulate gene expression that is important for cholesterol and fatty acid metabolism. In addition to their roles in lipid metabolism, LXRs participate in the transcriptional regulation of macrophage activation and are considered potent regulators of inflammation.
- Research Article | SpotlightLiver X Receptor Nuclear Receptors Are Transcriptional Regulators of Dendritic Cell Chemotaxis