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membrane proteins

  • Open Access
    CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum
    Research Article | Spotlight
    CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum

    We previously described a mechanism of acquired resistance of B-cell acute lymphoblastic leukemia to CD19-directed chimeric antigen receptor T-cell (CART) immunotherapy. It was based on in-frame insertions in or skipping of CD19 exon 2.

    Asen Bagashev, Elena Sotillo, Chih-Hang Anthony Tang, Kathryn L. Black, Jessica Perazzelli, Steven H. Seeholzer, Yair Argon, David M. Barrett, Stephan A. Grupp, Chih-Chi Andrew Hu, Andrei Thomas-Tikhonenko
  • Research Article
    Acetylation of Cavin-1 Promotes Lipolysis in White Adipose Tissue
    Shui-Rong Zhou, Liang Guo, Xu Wang, Yang Liu, Wan-Qiu Peng, Yuan Liu, Xiang-Bo Wei, Xin Dou, Meng Ding, Qun-Ying Lei, Shu-Wen Qian, Xi Li, Qi-Qun Tang
  • Research Article
    Protein 4.1R Exon 16 3′ Splice Site Activation Requires Coordination among TIA1, Pcbp1, and RBM39 during Terminal Erythropoiesis
    Shu-Ching Huang, Henry S. Zhang, Brian Yu, Ellen McMahon, Dan T. Nguyen, Faye H. Yu, Alexander C. Ou, Jennie Park Ou, Edward J. Benz
  • Articles
    Spatial Regulation of Cyclic AMP-Epac1 Signaling in Cell Adhesion by ERM Proteins
    Martijn Gloerich, Bas Ponsioen, Marjolein J. Vliem, Zhongchun Zhang, Jun Zhao, Matthijs R. Kooistra, Leo S. Price, Laila Ritsma, Fried J. Zwartkruis, Holger Rehmann, Kees Jalink, Johannes L. Bos
  • Articles
    Analysis of Leigh Syndrome Mutations in the Yeast SURF1 Homolog Reveals a New Member of the Cytochrome Oxidase Assembly Factor Family
    Megan Bestwick, Mi-Young Jeong, Oleh Khalimonchuk, Hyung Kim, Dennis R. Winge
  • Articles | Spotlight
    Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras
    Atsuko Sakurai, Julie Gavard, Yuliya Annas-Linhares, John R. Basile, Panomwat Amornphimoltham, Todd R. Palmby, Hiroshi Yagi, Fan Zhang, Paul A. Randazzo, Xuri Li, Roberto Weigert, J. Silvio Gutkind
  • Articles
    A Novel Transcriptional Repressor, Rhit, Is Involved in Heat-Inducible and Age-Dependent Expression of Mpv17-Like Protein, a Participant in Reactive Oxygen Species Metabolism
    Reiko Iida, Misuzu Ueki, Toshihiro Yasuda
  • Articles
    Establishment of Extracellular Signal-Regulated Kinase 1/2 Bistability and Sustained Activation through Sprouty 2 and Its Relevance for Epithelial Function
    Weimin Liu, Kavita Tundwal, Qiaoling Liang, Nicholas Goplen, Sadee Rozario, Nayeem Quayum, Magdalena Gorska, Sally Wenzel, Silvana Balzar, Rafeul Alam
  • Articles
    Bax Inhibitor 1 Increases Cell Adhesion through Actin Polymerization: Involvement of Calcium and Actin Binding
    Geum-Hwa Lee, Taeho Ahn, Do-Sung Kim, Seoung Ju Park, Yong Chul Lee, Wan Hee Yoo, Sung Jun Jung, Jae-Seong Yang, Sanguk Kim, Andras Muhlrad, Young-Rok Seo, Soo-Wan Chae, Hyung-Ryong Kim, Han-Jung Chae
  • Articles
    Formation of the Redox Cofactor Centers during Cox1 Maturation in Yeast Cytochrome Oxidase
    Oleh Khalimonchuk, Megan Bestwick, Brigitte Meunier, Talina C. Watts, Dennis R. Winge

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