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methylation

  • Open Access
    Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation
    Research Article
    Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation

    The retrotransposon LINE-1 (L1) is a significant source of endogenous mutagenesis in humans. In each individual genome, a few retrotransposition-competent L1s (RC-L1s) can generate new heritable L1 insertions in the early embryo, primordial germ line, and germ cells.

    Carmen Salvador-Palomeque, Francisco J. Sanchez-Luque, Patrick R. J. Fortuna, Adam D. Ewing, Ernst J. Wolvetang, Sandra R. Richardson, Geoffrey J. Faulkner
  • Research Article
    TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival
    Joshua M. Dewe, Benjamin L. Fuller, Jenna M. Lentini, Stefanie M. Kellner, Dragony Fu
  • TRANSCRIPTIONAL REGULATION
    Methylation of Adjacent CpG Sites Affects Sp1/Sp3 Binding and Activity in the p21Cip1 Promoter
    Wei-Guo Zhu, Kanur Srinivasan, Zunyan Dai, Wenrui Duan, Lawrence J. Druhan, Haiming Ding, Lisa Yee, Miguel A. Villalona-Calero, Christoph Plass, Gregory A. Otterson
  • TRANSCRIPTIONAL REGULATION
    Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II
    Nevan J. Krogan, Minkyu Kim, Amy Tong, Ashkan Golshani, Gerard Cagney, Veronica Canadien, Dawn P. Richards, Bryan K. Beattie, Andrew Emili, Charles Boone, Ali Shilatifard, Stephen Buratowski, Jack Greenblatt
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