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Neoplasms

  • Research Article
    Effect of Mutant p53 Proteins on Glycolysis and Mitochondrial Metabolism
    Matilda Eriksson, Gorbatchev Ambroise, Amanda Tomie Ouchida, Andre Lima Queiroz, Dominique Smith, Alfredo Gimenez-Cassina, Marcin P. Iwanicki, Patricia A. Muller, Erik Norberg, Helin Vakifahmetoglu-Norberg
  • Open Access
    Research Article
    Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation
    Ayano Kondo, Aya Nonaka, Teppei Shimamura, Shogo Yamamoto, Tetsuo Yoshida, Tatsuhiko Kodama, Hiroyuki Aburatani, Tsuyoshi Osawa
  • Open Access
    Research Article
    Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors
    Raffaella Iurlaro, Franziska Püschel, Clara Lucía León-Annicchiarico, Hazel O'Connor, Seamus J. Martin, Daniel Palou-Gramón, Estefanía Lucendo, Cristina Muñoz-Pinedo
  • Research Article | Spotlight
    Interchangeable Roles for E2F Transcriptional Repression by the Retinoblastoma Protein and p27KIP1–Cyclin-Dependent Kinase Regulation in Cell Cycle Control and Tumor Suppression
    Michael J. Thwaites, Matthew J. Cecchini, Daniel T. Passos, Ian Welch, Frederick A. Dick
  • Articles
    Chromatin Loading of E2F-MLL Complex by Cancer-Associated Coregulator ANCCA via Reading a Specific Histone Mark
    Alexey S. Revenko, Ekaterina V. Kalashnikova, Abigael T. Gemo, June X. Zou, Hong-Wu Chen
  • Articles | Spotlight
    Widespread Overexpression of Epitope-Tagged Mdm4 Does Not Accelerate Tumor Formation In Vivo
    Sarah De Clercq, Agnieszka Gembarska, Geertrui Denecker, Marion Maetens, Michael Naessens, Katharina Haigh, Jody J. Haigh, Jean-Christophe Marine
  • Articles
    The H3K27me3 Demethylase dUTX Is a Suppressor of Notch- and Rb-Dependent Tumors in Drosophila
    Hans-Martin Herz, Laurence D. Madden, Zhihong Chen, Clare Bolduc, Eugene Buff, Ravi Gupta, Ramana Davuluri, Ali Shilatifard, Iswar K. Hariharan, Andreas Bergmann
  • Free
    Commentary
    p32 (C1QBP) and Cancer Cell Metabolism: Is the Warburg Effect a Lot of Hot Air?
    Chi V. Dang
  • Free
    Articles
    Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation
    Valentina Fogal, Adam D. Richardson, Priya P. Karmali, Immo E. Scheffler, Jeffrey W. Smith, Erkki Ruoslahti
  • Articles
    The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors
    Mark Watson, Anne Roulston, Laurent Bélec, Xavier Billot, Richard Marcellus, Dominique Bédard, Cynthia Bernier, Stéphane Branchaud, Helen Chan, Kenza Dairi, Karine Gilbert, Daniel Goulet, Michel-Olivier Gratton, Henady Isakau, Anne Jang, Abdelkrim Khadir, Elizabeth Koch, Manon Lavoie, Michael Lawless, Mai Nguyen, Denis Paquette, Émilie Turcotte, Alvin Berger, Matthew Mitchell, Gordon C. Shore, Pierre Beauparlant

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