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prions

  • Open Access
    Research Article
    Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance

    Prions of lower eukaryotes are transmissible protein particles that propagate by converting homotypic soluble proteins into growing protein assemblies. Prion activity is conferred by so-called prion domains, regions of low complexity that are often enriched in glutamines and asparagines (Q/N).

    Yvonne Duernberger, Shu Liu, Katrin Riemschoss, Lydia Paulsen, Romina Bester, Peer-Hendrik Kuhn, Manuel Schölling, Stefan F. Lichtenthaler, Ina Vorberg
  • Research Article
    Analysis of Small Critical Regions of Swi1 Conferring Prion Formation, Maintenance, and Transmission
    Stephanie Valtierra, Zhiqiang Du, Liming Li
  • Research Article
    Effects of Mutations on the Aggregation Propensity of the Human Prion-Like Protein hnRNPA2B1
    Kacy R. Paul, Amandine Molliex, Sean Cascarina, Amy E. Boncella, J. Paul Taylor, Eric D. Ross
  • Articles
    Distinct Subregions of Swi1 Manifest Striking Differences in Prion Transmission and SWI/SNF Function
    Zhiqiang Du, Emily T. Crow, Hyun Seok Kang, Liming Li
  • Articles
    Sti1 Regulation of Hsp70 and Hsp90 Is Critical for Curing of Saccharomyces cerevisiae [PSI+] Prions by Hsp104
    Michael Reidy, Daniel C. Masison
  • Articles
    Compositional Determinants of Prion Formation in Yeast
    James A. Toombs, Blake R. McCarty, Eric D. Ross
  • Articles
    A Regulatory Role of the Rnq1 Nonprion Domain for Prion Propagation and Polyglutamine Aggregates
    Hiroshi Kurahashi, Masao Ishiwata, Shoichiro Shibata, Yoshikazu Nakamura
  • Articles
    Prion Protein Repeat Expansion Results in Increased Aggregation and Reveals Phenotypic Variability
    Elizabeth M. H. Tank, David A. Harris, Amar A. Desai, Heather L. True
  • Articles
    Cell-Specific Metabolism and Pathogenesis of Transmembrane Prion Protein
    Yaping Gu, Xiu Luo, Subhabrata Basu, Hisashi Fujioka, Neena Singh
  • Articles
    Modulation of Prion Formation, Aggregation, and Toxicity by the Actin Cytoskeleton in Yeast
    Elena E. Ganusova, Laura N. Ozolins, Srishti Bhagat, Gary P. Newnam, Renee D. Wegrzyn, Michael Y. Sherman, Yury O. Chernoff

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