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RNA polymerase III

  • Open Access
    Inhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic Acid
    Research Article | Spotlight
    Inhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic Acid

    Mycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil, a drug that is widely used for immunosuppression in organ transplantation and autoimmune diseases, as well as anticancer chemotherapy. It inhibits IMP dehydrogenase, a rate-limiting enzyme in de novo synthesis of guanidine nucleotides.

    Aneta Jurkiewicz, Ewa Leśniewska, Małgorzata Cieśla, Neuton Gorjão, Theodoros Kantidakis, Robert J. White, Magdalena Boguta, Damian Graczyk
  • Research Article
    Functions of the TFIIE-Related Tandem Winged-Helix Domain of Rpc34 in RNA Polymerase III Initiation and Elongation
    Yi-Yu Wei, Hung-Ta Chen
  • Articles | Spotlight
    mTORC1 Directly Phosphorylates and Regulates Human MAF1
    Annemieke A. Michels, Aaron M. Robitaille, Diane Buczynski-Ruchonnet, Wassim Hodroj, Jaime H. Reina, Michael N. Hall, Nouria Hernandez
  • Articles
    TLS Inhibits RNA Polymerase III Transcription
    Adelene Y. Tan, James L. Manley
  • Articles
    Sub1 Functions in Osmoregulation and in Transcription by both RNA Polymerases II and III
    Emanuel Rosonina, Ian M. Willis, James L. Manley
  • Articles
    Different Functional Modes of p300 in Activation of RNA Polymerase III Transcription from Chromatin Templates
    Claudia Mertens, Robert G. Roeder
  • Articles
    PTEN Represses RNA Polymerase III-Dependent Transcription by Targeting the TFIIIB Complex
    Annette Woiwode, Sandra A. S. Johnson, Shuping Zhong, Cheng Zhang, Robert G. Roeder, Martin Teichmann, Deborah L. Johnson
  • Articles
    Chromatin Structure and Expression of a Gene Transcribed by RNA Polymerase III Are Independent of H2A.Z Deposition
    Aneeshkumar Gopalakrishnan Arimbasseri, Purnima Bhargava
  • Articles
    Maf1 Is Involved in Coupling Carbon Metabolism to RNA Polymerase III Transcription
    Małgorzata Cieśla, Joanna Towpik, Damian Graczyk, Danuta Oficjalska-Pham, Olivier Harismendy, Audrey Suleau, Karol Balicki, Christine Conesa, Olivier Lefebvre, Magdalena Boguta
  • Articles
    Role of RNA Polymerase III Transcription Factors in the Selection of Integration Sites by the Dictyostelium Non-Long Terminal Repeat Retrotransposon TRE5-A
    Oliver Siol, Moustapha Boutliliss, Thanh Chung, Gernot Glöckner, Theodor Dingermann, Thomas Winckler

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