RNA polymerase III
Research Article | SpotlightInhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic AcidMycophenolic acid (MPA) is the active metabolite of mycophenolate mofetil, a drug that is widely used for immunosuppression in organ transplantation and autoimmune diseases, as well as anticancer chemotherapy. It inhibits IMP dehydrogenase, a rate-limiting enzyme in de novo synthesis of guanidine nucleotides.
- Articles | SpotlightmTORC1 Directly Phosphorylates and Regulates Human MAF1