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Ubiquitin-Protein Ligases

  • GENE EXPRESSION
    Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex
    Donna D. Zhang, Shih-Ching Lo, Janet V. Cross, Dennis J. Templeton, Mark Hannink
  • GENE EXPRESSION
    Both BC-Box Motifs of Adenovirus Protein E4orf6 Are Required To Efficiently Assemble an E3 Ligase Complex That Degrades p53
    Paola Blanchette, Chi Ying Cheng, Qin Yan, Gary Ketner, David A. Ornelles, Thomas Dobner, Ronald C. Conaway, Joan Weliky Conaway, Philip E. Branton
  • CELL GROWTH AND DEVELOPMENT
    BRUCE, a Giant E2/E3 Ubiquitin Ligase and Inhibitor of Apoptosis Protein of the trans-Golgi Network, Is Required for Normal Placenta Development and Mouse Survival
    Kristina Lotz, George Pyrowolakis, Stefan Jentsch
  • CELL GROWTH AND DEVELOPMENT
    Notch-Induced E2A Degradation Requires CHIP and Hsc70 as Novel Facilitators of Ubiquitination
    Zhong Huang, Lei Nie, Min Xu, Xiao-Hong Sun
  • CELL GROWTH AND DEVELOPMENT
    Alix/AIP1 Antagonizes Epidermal Growth Factor Receptor Downregulation by the Cbl-SETA/CIN85 Complex
    Mirko H. H. Schmidt, Daniela Hoeller, Jiuhong Yu, Frank B. Furnari, Webster K. Cavenee, Ivan Dikic, Oliver Bögler
  • CELL GROWTH AND DEVELOPMENT
    Regulation and Recognition of SCFGrr1 Targets in the Glucose and Amino Acid Signaling Pathways
    Nathalie Spielewoy, Karin Flick, Tatyana I. Kalashnikova, John R. Walker, Curt Wittenberg
  • CELL GROWTH AND DEVELOPMENT
    Vhlh Gene Deletion Induces Hif-1-Mediated Cell Death in Thymocytes
    Mangatt P. Biju, Aaron K. Neumann, Steven J. Bensinger, Randall S. Johnson, Laurence A. Turka, Volker H. Haase
  • CELL GROWTH AND DEVELOPMENT
    The Keap1-BTB Protein Is an Adaptor That Bridges Nrf2 to a Cul3-Based E3 Ligase: Oxidative Stress Sensing by a Cul3-Keap1 Ligase
    Sara B. Cullinan, John D. Gordan, Jianping Jin, J. Wade Harper, J. Alan Diehl
  • CELL GROWTH AND DEVELOPMENT
    Ubiquitination and Proteolysis of Cancer-Derived Smad4 Mutants by SCFSkp2
    Min Liang, Yao-Yun Liang, Katharine Wrighton, Dana Ungermannova, Xiao-Ping Wang, F. Charles Brunicardi, Xuedong Liu, Xin-Hua Feng, Xia Lin
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Edd, the Murine Hyperplastic Disc Gene, Is Essential for Yolk Sac Vascularization and Chorioallantoic Fusion
    Darren N. Saunders, Samantha L. Hird, Sarah L. Withington, Sally L. Dunwoodie, Michelle J. Henderson, Christine Biben, Robert L. Sutherland, Christopher J. Ormandy, Colin K. W. Watts

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