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Ubiquitin-Protein Ligases

  • TRANSCRIPTIONAL REGULATION
    Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2
    Akira Kobayashi, Moon-Il Kang, Hiromi Okawa, Makiko Ohtsuji, Yukari Zenke, Tomoki Chiba, Kazuhiko Igarashi, Masayuki Yamamoto
  • CELL GROWTH AND DEVELOPMENT
    pVHL Modification by NEDD8 Is Required for Fibronectin Matrix Assembly and Suppression of Tumor Development
    Natalie H. Stickle, Jacky Chung, Jeffery M. Klco, Richard P. Hill, William G. Kaelin, Michael Ohh
  • CELL AND ORGANELLE STRUCTURE AND ASSEMBLY
    Participation of the Ubiquitin-Conjugating Enzyme UBE2E3 in Nedd4-2-Dependent Regulation of the Epithelial Na+ Channel
    Christophe Debonneville, Olivier Staub
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    Np95 Is a Histone-Binding Protein Endowed with Ubiquitin Ligase Activity
    Elisabetta Citterio, Roberto Papait, Francesco Nicassio, Manuela Vecchi, Paola Gomiero, Roberto Mantovani, Pier Paolo Di Fiore, Ian Marc Bonapace
  • TRANSCRIPTIONAL REGULATION
    CHIP Mediates Degradation of Smad Proteins and Potentially Regulates Smad-Induced Transcription
    Linyu Li, Hong Xin, Xialian Xu, Mei Huang, Xinjun Zhang, Yue Chen, Shuping Zhang, Xin-Yuan Fu, Zhijie Chang
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway
    Yong Tae Kwon, Zanxian Xia, Jee Young An, Takafumi Tasaki, Ilia V. Davydov, Jai Wha Seo, Jun Sheng, Youming Xie, Alexander Varshavsky
  • DNA DYNAMICS AND CHROMOSOME STRUCTURE
    BARD1 Participates with BRCA1 in Homology-Directed Repair of Chromosome Breaks
    Ulrica K. Westermark, Marsha Reyngold, Adam B. Olshen, Richard Baer, Maria Jasin, Mary Ellen Moynahan
  • GENE EXPRESSION
    Influence of the RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells
    Stefanie Galbán, Jennifer L. Martindale, Krystyna Mazan-Mamczarz, Isabel López de Silanes, Jinshui Fan, Wengong Wang, Jochen Decker, Myriam Gorospe
  • GENE EXPRESSION
    Hypoxia-Induced Gene Expression Occurs Solely through the Action of Hypoxia-Inducible Factor 1α (HIF-1α): Role of Cytoplasmic Trapping of HIF-2α
    Sang-ki Park, Agnes M. Dadak, Volker H. Haase, Lucrezia Fontana, Amato J. Giaccia, Randall S. Johnson
  • MAMMALIAN GENETIC MODELS WITH MINIMAL OR COMPLEX PHENOTYPES
    Loss of Bard1, the Heterodimeric Partner of the Brca1 Tumor Suppressor, Results in Early Embryonic Lethality and Chromosomal Instability
    Ellen E. McCarthy, Julide T. Celebi, Richard Baer, Thomas Ludwig

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